CNOT6L codes for the CCR4-NOT transcription complex subunit 6 like protein which has 63 kDa (63,001 Da - isoform 1). It has hydrolase and catalytic activities. It is invovled in mrna processing and silencing of regulatory ncrna-mediated genes.
hydrolase activity; catalytic activity (acting on rna)
Used cell type
HEK293T; HeLa
Used Stimuli
sodium arsenite
Subcellular Localization
nucleus; cytoplasm
Reference
Youn, J.-Y., Dunham, W. H., Hong, S. J., Knight, J. D. R., Bashkurov, M., Chen, G. I., … Gingras, A.-C. (2018). High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies. Molecular Cell, 69(3), 517–532.e11.