ASCC1

Activating signal cointegrator 1 complex subunit 1

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    Description

    ASCC1 is a protein with 45 kDa (45,509 - isoform 1). It is a rna binding protein. It is involved in dna repair mechanisms and regulation of dna-templated transcription.

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    Details
    • Complete Protein Name
      Activating signal cointegrator 1 complex subunit 1
    • Gene ID
      51008
    • Uniprot ID
      Q8N9N2
    • Chromossomal Location
      10q22.1
    • RNA-binding protein
      Yes
    • Molecular Function
      rna binding
    • OMIM Disease
      Barrett esophagus/esophageal adenocarcinoma; Spinal muscular atrophy with congenital bone fractures 2
    • Used cell type
      HEK293T; iPSCs
    • Used Stimuli
      sodium arsenite
    • Subcellular Localization
      nucleus; nucleus speckle
    • Reference
      Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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