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    ASCC1

    Activating signal cointegrator 1 complex subunit 1

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      Description

      ASCC1 is a protein with 45 kDa (45,509 - isoform 1). It is a rna binding protein. It is involved in dna repair mechanisms and regulation of dna-templated transcription.

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      Details
      • Complete Protein Name
        Activating signal cointegrator 1 complex subunit 1
      • Gene ID
        51008
      • Uniprot ID
        Q8N9N2
      • Chromossomal Location
        10q22.1
      • RNA-binding protein
        Yes
      • Molecular Function
        rna binding
      • OMIM Disease
        Barrett esophagus/esophageal adenocarcinoma; Spinal muscular atrophy with congenital bone fractures 2
      • Used cell type
        HEK293T; iPSCs; HeLa; HepG2
      • Used Stimuli
        puromycin, thapsigargin, heat shock, sodium arsenite
      • Subcellular Localization
        nucleus; nucleus speckle
      • Reference
        Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, Bennett EJ, Lécuyer E, Yeo GW. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 2018 Jan 25;172(3):590-604.e13.
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