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    AKAP8

    A-kinase anchoring protein 8

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      Description

      AKAP8 is a protein with 76 kDa. It is a rna and dna binding protein. It is involved in the cell mitotic cycle, mitotic nuclear division, in immune system processes, chromosome segregation and cell signaling.

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      Details
      • Complete Protein Name
        A-kinase anchoring protein 8
      • Gene ID
        10270
      • Uniprot ID
        O43823
      • Chromossomal Location
        19p13.12
      • RNA-binding protein
        Yes
      • Molecular Function
        rna binding; dna binding
      • Used cell type
        U-2 OS
      • Used Stimuli
        sodium arsenite
      • Subcellular Localization
        nucleus; nucleolus; cytoplasm
      • Reference
        Marmor-Kollet H, Siany A, Kedersha N, Knafo N, Rivkin N, Danino YM, Moens TG, Olender T, Sheban D, Cohen N, Dadosh T, Addadi Y, Ravid R, Eitan C, Toth Cohen B, Hofmann S, Riggs CL, Advani VM, Higginbottom A, Cooper-Knock J, Hanna JH, Merbl Y, Van Den Bosch L, Anderson P, Ivanov P, Geiger T, Hornstein E. Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis. Mol Cell. 2020 Dec 3;80(5):876-891.e6.
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